PHYB GENI RNAi QILINGAN G'O'ZA LINIYALARIDA CpG, CHG VA CHH METILLANISH SHAKLLARINING QIYOSIY TAHLILI

Nurdinjon Obidov

doi:10.5281/zenodo.23227246

Pdf Zenodo

Published: 2026-09-25

DOI: https://doi.org/10.5281/zenodo.23227246

Keywords:

Gossypium hirsutum L., PHYB, RNAi, DNK metillanishi, CpG, CHG, CHH, WGBS, DMR, epigenom, RdDM, transpozon

Obidov Nurdinjon Shuhratjon o’g’li, Ayubov Mirzakamol Sobitjonovich, Mamajonov Bexzod Orifjon o’g’li, Yusupov Abduraxmon Nodirjon o’g’li, Murodov Anvarjon Adhamjon o’g’li, Bashirxonov Ziyodullaxon Hakimullox o’g’li

Abstract

DNK metillanishi o‘simlik genomining strukturaviy va funksional holatini boshqaruvchi muhim epigenetik mexanizmlardan biridir. O‘simliklarda sitozinning metillanishi asosan CpG, CHG va CHH kontekstlarida amalga oshadi. Ushbu kontekstlar molekulyar mexanizmi, genomdagi taqsimlanishi va biologik funksiyasi jihatidan farqlanadi. CpG va CHG metillanishi simmetrik, CHH metillanishi esa assimetrik kontekstda sodir bo‘ladi. G‘o‘zada DNK metillanishi gen ekspressiyasi, transpozonlar faolligi, genom barqarorligi va qimmatli xo’jalik belgilarini rivojlanishini boshqarishda muhim ahamiyatga ega. Mazkur maqolada Gossypium hirsutum L. PHYB-RNAi tizmalarining genomidagi metillanish xususiyatlari, ularning molekulyar mexanizmlari va WGBS yordamida qiyosiy tahlil qilish imkoniyatlari yoritilgan. Shuningdek, differensial metillangan hududlarni aniqlash hamda metillanish o‘zgarishlarini gen ekspressiyasi bilan bog‘lash masalalari ko‘rib chiqilgan.

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Vol. 1 No. 1 (2026): Kompyuter ilmlari va muhandislik texnologiyalari. Xalqaro ilmiy-texnik anjuman 1-qism

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How to Cite

Obidov , N. (2026). PHYB GENI RNAi QILINGAN G’O’ZA LINIYALARIDA CpG, CHG VA CHH METILLANISH SHAKLLARINING QIYOSIY TAHLILI. Konferensiyalar, 1(1), 269-271. https://doi.org/10.5281/zenodo.23227246

References

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Fan, W., et al. (2017). Single-base resolution methylomes of upland cotton (Gossypium hirsutum L.) reveal epigenome modifications in response to drought stress. BMC Genomics, 18, 386. https://doi.org/10.1186/s12864-017-3681-y.

Abdurakhmonov, I. Y., Buriev, Z. T., Saha, S., Jenkins, J. N., Abdukarimov, A., & Pepper, A. E. (2014). Phytochrome RNAi enhances major fibre quality and agronomic traits of the cotton Gossypium hirsutum L. Nature Communications, 5, 3062. https://doi.org/10.1038/ncomms4062.

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